Clinically grounded

GLP-1 guides

Every number here traces to a published clinical trial. No estimates, no blending studies. Just what the data actually says.

Wegovy semaglutide 2.4mg
STEP 1 · 2021
14.9%avg. weight loss

How Much Weight Can You Lose on Wegovy?

The STEP 1 trial enrolled 1,961 people for 68 weeks. Average loss was 14.9% of body weight. Here is the full distribution, broken down by starting weight.

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Comparison tirzepatide vs semaglutide
STEP 1 + SURMOUNT-1
+6pptirzepatide advantage

Mounjaro vs Wegovy: What the Clinical Trials Show

Tirzepatide averaged 20.9% weight loss in SURMOUNT-1. Semaglutide 2.4mg averaged 14.9% in STEP 1. A straight read of both trials, including why you cannot compare them directly.

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All drugs pricing guide · 2026
Updated May 2026
$0min. with savings card

How Much Do GLP-1 Drugs Actually Cost?

List price, GoodRx, manufacturer savings cards, insurance, and telehealth. Every pricing path for Wegovy, Zepbound, Mounjaro, and Ozempic, with what changed after the FDA shortage ended.

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